As we age, our skincare routines are likely to change. Along with the best cleansers and moisturising day creams, the best anti-ageing serums could be worth a spot in your lineup. These targeted formulas are designed to tackle specific signs of ageing, delivering high concentrations of actives in fast-absorbing, weightless textures.
The best anti-ageing serums blend proven ingredients such as vitamin C for brightness, peptides to support skin structure, hyaluronic acid for bounce and repair, and nourishing omega oils to keep dryness at bay. Used sparingly (a pea-sized amount is plenty) these concentrates are designed to smooth fine lines, soften texture and help skin look firmer and more even over time.
Prices range from purse-friendly to premium, but high cost doesn’t always mean more noticeable results. Below, I’ve tested a bunch of anti-ageing serums to pin down the ones that are actually worth your time and money.
Read more: Best moisturisers for mature skin, tested by a beauty writer in her 50s
The best anti-ageing serums for 2026 are:
- Best overall – Q&A collagen booster serum: £12, Amazon.co.uk
- Best for dark spots – Cetaphil healthy radiance brightening serum: £30, Boots.com
- Best for 50+ skin – Skinceuticals P-Tiox wrinkle-modulating peptide serum: £135, Cultbeauty.co.uk
- Best makeup artist favourite – Estee Lauder advanced night repair multi recovery serum: £89, Boots.com
How I tested

I tested each of the reviewed products for at least three weeks. I used some daily in the morning and evening, others twice weekly – both of which are recommended by the beauty glitterati. Some formulas are historical favourites of mine and others are brand new. As they have high-potency ingredients, build up to using twice daily over a few weeks (especially if you have sensitive skin) and target specific areas – lines, crow’s feet, wrinkles and dry spots or melasma – to see a positive difference. You can read more about my testing process and criteria at the end of this article.
Read more: I’m a 57-year-old beauty editor and these are the best eye creams for mature skin
